Company Announcements

LEI: 549300Q7EXQQH6KF7Z84

02 October 2024

RTW Biotech Opportunities Ltd

New Investment in Aktis Oncology

RTW Biotech Opportunities Ltd (the "Company"), a London Stock Exchange-listed investment company focused on identifying transformative assets with high growth potential across the life sciences sector, is pleased to note a new investment in Aktis Oncology ("Aktis").

The Company, alongside other investment vehicles managed by RTW Investments, LP (the "Investment Manager"), co-led Aktis's Series B round, raising $175 million in an oversubscribed and upsized financing to further advance its proprietary radiopharmaceutical pipeline. The funding will be used to further advance the company's differentiated radiopharmaceuticals pipeline, including its first-in-class Nectin-4-targeted miniprotein radioconjugate.

Aktis is a clinical-stage biotechnology company pioneering the discovery and development of novel targeted alpha radiopharmaceuticals to treat a broad range of solid tumours.

Roderick Wong, Managing Partner and CIO at the Investment Manager said, "We are thrilled to invest in Aktis Oncology, a leader in the development of novel targeted alpha radiopharmaceuticals. Their innovative approach to treating solid tumours demonstrates a significant advancement in cancer therapy. We believe in their mission and are confident that their miniprotein radioconjugate platform and experienced team will bring transformative treatments to patients in need. Our investment underscores our commitment to supporting pioneering companies that are making remarkable strides in oncology."

The full text of the announcement can be accessed at: https://aktisoncology.com/.

For Further Information

About Biotech Opportunities Ltd:

RTW Biotech Opportunities Ltd (LSE: RTW & RTWG) is an investment fund focused on identifying transformative assets with high growth potential across the biopharmaceutical and medical technology sectors. Driven by a long-term approach to support innovative businesses, RTW Biotech Opportunities Ltd invests in companies developing next-generation therapies and technologies that can significantly improve patients' lives. RTW Biotech Opportunities Ltd is managed by RTW Investments, LP, a leading healthcare-focused entrepreneurial investment firm with deep scientific expertise and a strong track record of supporting companies developing life-changing therapies.

Visit the website at www.rtwfunds.com/rtw-biotech-opportunities-ltd for more information.

***********

The information in this announcement may include forward-looking statements, which are based on the current expectations and projections about future events, and in certain cases can be identified by the use of terms such as "may", "will", "should", "expect", "anticipate", "project", "estimate", "intend", "continue", "target", "believe" (or the negatives thereon) or other variations thereon or comparable terminology. These forward-looking statements, as well as those included in any related materials, are subject to risks, uncertainties and assumptions about the Company and/or its underlying investments, including, among other things, the development of the applicable entity's business, trends in its operating industry, expected use of financing proceeds and future capital expenditures and acquisitions. In light of these risks, uncertainties and assumptions, the events in the forward-looking statements may not occur.

The information contained in this announcement is given at the date of its publication (unless otherwise marked). No reliance may be placed for any purpose whatsoever on the information or opinions contained in this announcement or on its completeness, accuracy or fairness.

***********