10x Genomics Delivers 'Single Cell for a Single Cent' with New Chromium Launches
These launches are part of the company's strategy to drive widespread adoption of single cell analysis by lowering customer costs in multiple directions: per cell, per sample, per experiment and per project. With these advances,
"These launches are an integral part of our ongoing push to democratize single cell analysis and make it more accessible and more affordable for more researchers than ever before," said
GEM-X Flex: Superior performance and ultra low cost per cell
GEM-X Flex Gene Expression
brings
Since its initial launch in 2022, Chromium Flex has delivered class-leading performance across a broad range of sample types and became the first and only commercial single cell assay compatible with FFPE samples. Now on the GEM-X architecture, Flex adds the scalability to run millions of cells for less than
Key Performance Specifications:
- Ultimate flexibility for low cost at any scale: Researchers can benefit from the highest sequencing efficiency to reduce total project costs, as well as fix, batch and run samples on their own schedule without compromising on data quality.
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Built for mega scale: With GEM-X Flex, researchers can profile up to 2.5 million cells per run and 5 million cells per kit, for a cost as low as
$0.01 per cell. - Unlock previously inaccessible sample types: Flex is the only single cell assay compatible with a wide range of sample types: fresh, frozen, PFA-fixed tissue, whole blood, and FFPE samples.
- Improved sample recovery: With new input recommendations as low as 25,000 cells per sample, GEM-X Flex delivers a four-fold improvement in sample recovery and enables researchers to explore limited samples like small tissue biopsies and flow-sorted cells.
"Chromium Flex has set a new standard in routine sample preservation for our core facility users, offering a flexible and reliable way to preserve biological material for future analysis. We've already sequenced hundreds of samples and likely have a multitude more biobanked in the freezer, ready for future studies," said
GEM-X Flex Gene Expression, compatible exclusively with Chromium iX and X instruments, is now shipping to customers globally.
GEM-X Universal Multiplex: Easy on-chip multiplexing delivers significantly lower per sample cost
With GEM-X Universal Multiplex, researchers can batch and run four independent samples, up to 5,000 cells per sample, for approximately
Key Performance Specifications:
- Exceptional performance and superior data quality: GEM-X Universal Multiplex delivers performance consistent with the company's flagship GEM-X 3' and 5' Gene Expression kits.
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Significantly lower per sample cost: Perform single cell analysis for approximately
$560 per sample, expanding access to a wider range of labs and research projects. - Broad sample compatibility: Analyze diverse species and sample types incompatible with other multiplexing methods. The GEM-X Universal 3' and 5' assays are also compatible with upstream fixation for flexible sample processing and storage.
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Easy multiplexing workflow:
10x Genomics' unique, on-chip multiplexing workflow eliminates the need for upstream sample tagging and enables high cell recovery with low cell input requirements, ideally suited for limited samples including organoids and stem cells.
"GEM-X Universal Multiplex not only drives large-scale, high-throughput projects, but also lowers barriers for new users," added Vandamme. "Its clean multiplexing strategy enables affordable entry into the field without the complexity of additional labeling requirements, making it ideal for pilot experiments and easier to scale. On-chip multiplexing simplifies workflows while making single cell sequencing more accessible to all."
GEM-X Universal 3' Gene Expression Multiplex is compatible with Chromium Xo and X instruments. GEM-X Universal 5' Gene Expression Multiplex is exclusively available on Chromium X instruments. All GEM-X Universal Multiplex assays are now available for pre-order and are expected to begin shipping later this quarter.
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