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About the company
Annovis Bio, Inc. is a late-stage clinical drug platform company addressing neurodegeneration such as Alzheimer’s disease (AD), and Parkinson’s disease (PD). The Company is developing its lead product candidate, Buntanetap, which is designed to address AD, PD, and potentially other chronic neurodegenerative diseases. Buntanetap is a synthetically produced small molecule, orally administered, brain penetrant compound. Its product candidate ANVS405 is an intravenous drug being developed for acute indications and focused on protecting the brain after traumatic brain injury and/or stroke. ANVS405 is the same compound as Buntanetap, given in cases of acute head and brain trauma. ANVS301 is an orally administered drug being developed to increase cognitive capability in later stages of AD and dementia. ANVS301 is observed to improve memory and learning in very old rats by lowering the number of errors from over six to three.
- Revenue in USD (TTM)0.00
- Net income in USD-24.88m
- Incorporated2008
- Employees8.00
- LocationAnnovis Bio Inc101 LINDENWOOD DRIVE, SUITE 225MALVERN 19355United StatesUSA
- Phone+1 (484) 875-3192
- Fax+1 (610) 727-4001
- Websitehttps://www.annovisbio.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Metagenomi Therapeutics Inc | 30.91m | -88.74m | 54.80m | 124.00 | -- | 0.3072 | -- | 1.77 | -2.39 | -2.39 | 0.8308 | 4.75 | 0.102 | -- | 39.91 | 153,034.70 | -29.27 | -- | -33.42 | -- | -- | -- | -287.06 | -- | -- | -- | 0.00 | -- | 16.84 | -- | -14.36 | -- | -- | -- |
| Grace Therapeutics, Inc | 0.00 | -5.98m | 55.86m | 32.00 | -- | 0.8608 | -- | -- | -0.3607 | -0.3607 | 0.00 | 4.19 | 0.00 | -- | -- | -- | -9.22 | -24.13 | -9.46 | -25.07 | -- | -- | -- | -48,136.22 | -- | -- | 0.00 | -- | -- | -- | 25.56 | -- | -- | -- |
| Tevogen Bio Holdings Inc | 0.00 | -31.42m | 56.40m | 18.00 | -- | -- | -- | -- | -0.2138 | -0.2138 | 0.00 | -0.0396 | 0.00 | -- | -- | 0.00 | -706.86 | -- | -- | -- | -- | -- | -- | -- | -- | -231.10 | -- | -- | -- | -- | 83.01 | -- | -- | -- |
| PMV Pharmaceuticals Inc | 0.00 | -82.71m | 59.06m | 63.00 | -- | 0.4861 | -- | -- | -1.58 | -1.58 | 0.00 | 2.28 | 0.00 | -- | -- | 0.00 | -46.29 | -21.46 | -49.90 | -22.32 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 14.87 | -- | 43.14 | -- |
| RetinalGenix Technologies Inc | 0.00 | -2.67m | 59.54m | 0.00 | -- | -- | -- | -- | -0.1455 | -0.1455 | 0.00 | -0.1168 | 0.00 | -- | -- | -- | -5,576.42 | -14,417.91 | -- | -- | -- | -- | -- | -- | -- | -684.26 | -- | -- | -- | -- | -106.65 | -- | -- | -- |
| Annovis Bio Inc | 0.00 | -24.88m | 62.81m | 8.00 | -- | 3.64 | -- | -- | -1.41 | -1.41 | 0.00 | 0.6517 | 0.00 | -- | -- | 0.00 | -157.74 | -116.87 | -221.93 | -138.75 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 56.25 | -- | -- | -- |
| Fractyl Health Inc | 3.00k | -122.20m | 64.17m | 107.00 | -- | -- | -- | 21,390.29 | -2.27 | -2.27 | 0.00006 | -0.024 | 0.00002 | -- | -- | 28.04 | -101.33 | -78.52 | -118.18 | -97.44 | 100.00 | -- | -4,073,233.00 | -122,747.90 | -- | -31.40 | 1.12 | -- | -22.50 | -- | 25.29 | -- | 78.65 | -- |
| Adicet Bio Inc | 0.00 | -115.01m | 66.19m | 152.00 | -- | 0.3294 | -- | -- | -20.22 | -20.22 | 0.00 | 20.98 | 0.00 | -- | -- | 0.00 | -59.52 | -36.24 | -66.08 | -39.41 | -- | -- | -- | -813.80 | -- | -- | 0.0088 | -- | -- | -- | 17.90 | -- | 32.77 | -- |
| Gain Therapeutics Inc | 0.00 | -19.39m | 69.62m | 23.00 | -- | 11.02 | -- | -- | -0.6364 | -0.6364 | 0.00 | 0.1643 | 0.00 | -- | -- | 0.00 | -153.07 | -79.58 | -234.03 | -95.32 | -- | -- | -- | -19,975.78 | -- | -33.79 | 0.067 | -- | -100.00 | -- | 8.34 | -- | 10.39 | -- |
| Coeptis Therapeutics Holdings Inc | 500.99k | -11.28m | 69.78m | 5.00 | -- | 6.03 | -- | 139.29 | -3.47 | -3.47 | 0.1476 | 2.01 | 0.0433 | -- | 11.65 | 100,198.00 | -118.13 | -42.24 | -167.86 | -44.32 | 72.96 | -- | -2,727.81 | -- | -- | -73.66 | 0.0224 | -- | -- | -- | 53.85 | -- | -- | -- |
| Spruce Biosciences Inc | 697.00k | -47.88m | 70.95m | 9.00 | -- | 6.94 | -- | 101.80 | -84.64 | -84.64 | 1.22 | 9.56 | 0.0173 | -- | -- | 33,190.48 | -119.08 | -43.45 | -161.94 | -49.92 | -- | -- | -6,869.30 | -1,459.77 | -- | -353.48 | 0.091 | -- | -51.32 | -- | -10.68 | -- | -- | -- |
| Maia Biotechnology Inc | 0.00 | -22.34m | 71.10m | 13.00 | -- | 1,587.38 | -- | -- | -0.7504 | -0.7504 | 0.00 | 0.0012 | 0.00 | -- | -- | 0.00 | -212.50 | -208.29 | -602.02 | -373.18 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -17.61 | -- | -- | -- |
Data as of Feb 13 2026. Currency figures normalised to Annovis Bio Inc's reporting currency: US Dollar USD
7.53%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| The Vanguard Group, Inc.as of 31 Dec 2025 | 779.97k | 2.94% |
| Susquehanna Financial Group LLLPas of 30 Sep 2025 | 218.42k | 0.82% |
| Geode Capital Management LLCas of 30 Sep 2025 | 184.15k | 0.70% |
| Citadel Securities LLCas of 30 Sep 2025 | 174.35k | 0.66% |
| D.A. Davidson & Co. (Investment Management)as of 31 Dec 2025 | 160.78k | 0.61% |
| Vanguard Fiduciary Trust Co.as of 31 Dec 2025 | 132.04k | 0.50% |
| Northern Trust Investments, Inc.(Investment Management)as of 30 Sep 2025 | 112.75k | 0.43% |
| Merit Financial Group LLCas of 31 Dec 2025 | 81.32k | 0.31% |
| BlackRock Fund Advisorsas of 30 Sep 2025 | 80.68k | 0.30% |
| PSM Verm�gensverwaltung GmbH Langen v.d.Goltz, Dr. Prinzas of 28 Nov 2025 | 70.00k | 0.26% |
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Data from 30 Sep 2025 - 31 Dec 2025Source: FactSet Research Systems Inc.
