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About the company
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
- Revenue in USD (TTM)-333.00k
- Net income in USD-161.09m
- Incorporated2016
- Employees31.00
- LocationApplied Therapeutics Inc545 FIFTH AVENUE, SUITE 1400NEW YORK 10017United StatesUSA
- Phone+1 (212) 220-9226
- Fax+1 (302) 636-5454
- Websitehttps://www.appliedtherapeutics.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Erasca Inc | 0.00 | -158.28m | 816.44m | 126.00 | -- | 1.75 | -- | -- | -0.9207 | -0.9207 | 0.00 | 1.65 | 0.00 | -- | -- | 0.00 | -32.76 | -- | -34.48 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 48.50 | -- | -- | -- |
| Dianthus Therapeutics Inc | 4.12m | -56.68m | 821.92m | 53.00 | -- | 2.29 | -- | 199.59 | -5.54 | -5.54 | 0.2092 | 12.20 | 0.0184 | -- | -- | 77,698.11 | -25.33 | -41.40 | -26.15 | -44.70 | -- | -- | -1,376.42 | -12,132.27 | -- | -- | 0.00 | -- | -- | -- | 43.04 | -- | -57.21 | -- |
| Arrivent Biopharma Inc | 0.00 | -74.89m | 833.27m | 40.00 | -- | 2.80 | -- | -- | -2.46 | -2.46 | 0.00 | 8.85 | 0.00 | -- | -- | 0.00 | -29.50 | -- | -31.02 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -87.86 | -- | -- | -- |
| Terns Pharmaceuticals Inc | 0.00 | -95.90m | 845.68m | 66.00 | -- | 3.22 | -- | -- | -1.31 | -1.31 | 0.00 | 3.11 | 0.00 | -- | -- | 0.00 | -36.84 | -41.34 | -38.72 | -45.70 | -- | -- | -- | -31,010.30 | -- | -- | 0.00 | -- | -- | -- | -49.49 | -- | -26.60 | -- |
| Silence Therapeutics plc | 23.85m | -53.42m | 852.48m | 115.00 | -- | 6.18 | -- | 35.75 | -0.4294 | -0.4294 | 0.1905 | 1.07 | 0.1273 | -- | 2.56 | 207,357.10 | -28.51 | -43.60 | -32.89 | -54.91 | 56.40 | -- | -224.01 | -287.30 | -- | -- | 0.0016 | -- | 44.99 | -- | -6.86 | -- | 156.10 | -- |
| 89bio Inc | 0.00 | -174.61m | 867.40m | 70.00 | -- | 1.67 | -- | -- | -1.97 | -1.97 | 0.00 | 4.91 | 0.00 | -- | -- | 0.00 | -32.50 | -45.50 | -34.68 | -49.31 | -- | -- | -- | -- | -- | -- | 0.0465 | -- | -- | -- | -39.37 | -- | -36.58 | -- |
| Oruka Therapeutics Inc | 0.00 | -7.20m | 874.96m | 4.00 | -- | 0.9278 | -- | -- | -5.97 | -5.97 | 0.00 | 26.94 | 0.00 | -- | -- | 0.00 | -19.22 | -27.78 | -19.99 | -29.38 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 46.21 | -- | -- | -- |
| Applied Therapeutics Inc | -333.00k | -161.09m | 884.32m | 31.00 | -- | 12.22 | -- | -- | -1.52 | -1.52 | -0.0029 | 0.6303 | -0.0039 | -- | -- | -13,320.00 | -187.94 | -140.37 | -467.74 | -240.93 | -- | -- | -- | -4,476.42 | -- | -- | 0.00 | -- | -- | -- | -45.15 | -- | -- | -- |
| Tango Therapeutics Inc | 42.51m | -116.49m | 889.30m | 140.00 | -- | 3.59 | -- | 20.92 | -1.11 | -1.11 | 0.4068 | 2.31 | 0.1118 | -- | -- | 303,635.70 | -30.62 | -- | -35.13 | -- | -- | -- | -274.04 | -- | -- | -- | 0.00 | -- | 46.93 | -- | 5.95 | -- | -- | -- |
| Perspective Therapeutics Inc | -1.87m | -49.02m | 892.07m | 116.00 | -- | 2.62 | -- | -- | -1.39 | -1.75 | -0.0437 | 5.06 | -0.0074 | -- | -- | -16,086.21 | -19.37 | -- | -20.14 | -- | -- | -- | -- | -- | -- | -- | 0.005 | -- | -- | -- | -- | -- | -- | -- |
| MiMedx Group Inc | 340.46m | 89.67m | 899.94m | 895.00 | 12.27 | 5.35 | 9.17 | 2.64 | 0.4996 | 0.4622 | 2.08 | 1.15 | 1.67 | 2.70 | 6.69 | 380,402.30 | 48.16 | -4.14 | 60.79 | -5.90 | 83.41 | 83.61 | 28.76 | -2.70 | 3.22 | 13.06 | 0.1028 | -- | 20.03 | -2.19 | 310.29 | -- | -26.47 | -- |
| Immunome Inc | 10.78m | -262.59m | 900.22m | 55.00 | -- | 3.54 | -- | 83.48 | -5.64 | -5.64 | 0.2591 | 4.23 | 0.0639 | -- | -- | 196,072.70 | -155.54 | -94.54 | -193.54 | -112.66 | -- | -- | -2,435.02 | -1,403.15 | -- | -- | 0.00 | -- | -- | -- | -184.68 | -- | 29.52 | -- |
| Zymeworks Inc | 62.71m | -112.51m | 930.01m | 290.00 | -- | 2.30 | -- | 14.83 | -1.52 | -1.52 | 0.8531 | 5.69 | 0.1122 | -- | 1.55 | 230,533.10 | -20.13 | -22.58 | -23.21 | -26.90 | -- | -- | -179.42 | -91.17 | -- | -- | 0.00008 | -- | -81.57 | 7.47 | -195.44 | -- | 3.58 | -- |
| Nuvation Bio Inc | 1.44m | -510.72m | 937.38m | 167.00 | -- | 2.39 | -- | 653.23 | -2.11 | -2.11 | 0.0064 | 2.43 | 0.0023 | -- | 0.4216 | 28,137.26 | -82.63 | -16.27 | -87.18 | -16.65 | 6.13 | -- | -35,590.24 | -- | -- | -- | 0.0214 | -- | -- | -- | 27.25 | -- | -- | -- |
| Sana Biotechnology Inc | 0.00 | -244.90m | 945.48m | 328.00 | -- | 2.78 | -- | -- | -1.15 | -1.15 | 0.00 | 1.53 | 0.00 | -- | -- | 0.00 | -36.94 | -38.99 | -42.11 | -42.70 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -5.11 | -- | 112.71 | -- |
Data as of Sep 20 2024. Currency figures normalised to Applied Therapeutics Inc's reporting currency: US Dollar USD
53.09%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Franklin Advisers, Inc.as of 30 Jun 2024 | 10.21m | 8.89% |
| Perceptive Advisors LLCas of 30 Jun 2024 | 8.01m | 6.97% |
| Janus Henderson Investors US LLCas of 30 Jun 2024 | 7.65m | 6.66% |
| Propel Bio Management LLCas of 30 Jun 2024 | 6.57m | 5.72% |
| BlackRock Fund Advisorsas of 30 Jun 2024 | 6.05m | 5.27% |
| Knoll Capital Management LPas of 30 Jun 2024 | 5.57m | 4.85% |
| Vestal Point Capital LPas of 30 Jun 2024 | 5.43m | 4.73% |
| The Vanguard Group, Inc.as of 30 Jun 2024 | 5.17m | 4.51% |
| Morgan Stanley & Co. LLCas of 30 Jun 2024 | 3.48m | 3.03% |
| Simplify Asset Management, Inc.as of 30 Jun 2024 | 2.82m | 2.45% |
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Data from 30 Jun 2024 - 30 Jun 2024Source: FactSet Research Systems Inc.
