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About the company
Denali Therapeutics Inc. is a biopharmaceutical company. The Company is focused on developing a portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for neurodegenerative diseases and lysosomal storage disease. The Company has a portfolio of both small molecule and biotherapeutic medicines, comprising seven product candidates in clinical development across seven indications as well as preclinical therapeutic candidates. Its three late-stage development programs include tividenofusp alfa (DNL310) for mucopolysaccharidosis II (MPS II); BIIB122/DNL151 (LRRK2 inhibitor) for Parkinson’s disease; and DNL343 (eIF2B activator) for amyotrophic lateral sclerosis (ALS). SAR443820/DNL788 (RIPK1 inhibitor) is being evaluated in a Phase II study for multiple sclerosis (MS). In addition, it has a Phase I/II study of TAK-594/DNL593 for frontotemporal dementia-granulin (FTD-GRN) and a Phase I/II study of DNL126 for MPS IIIA (Sanfilippo syndrome).
- Revenue in USD (TTM)1.27m
- Net income in USD-419.65m
- Incorporated2013
- Employees364.00
- LocationDenali Therapeutics Inc161 Oyster Point BlvdSOUTH SAN FRANCISCO 94080-1910United StatesUSA
- Phone+1 (650) 866-8548
- Fax+1 (302) 655-5049
- Websitehttps://www.denalitherapeutics.com
Peer analysis
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alvotech SA | 308.73m | -618.38m | 3.35bn | 999.00 | -- | -- | -- | 10.86 | -2.65 | -2.65 | 1.28 | -2.27 | 0.312 | 1.80 | 3.66 | 309,038.00 | -62.49 | -- | -222.85 | -- | 48.79 | -- | -200.30 | -- | 0.1569 | -0.2323 | 2.04 | -- | 9.84 | -- | -7.43 | -- | -- | -- |
Apogee Therapeutics Inc | 0.00 | -118.49m | 3.42bn | 91.00 | -- | 4.28 | -- | -- | -2.25 | -2.25 | 0.00 | 13.65 | 0.00 | -- | -- | 0.00 | -25.44 | -- | -26.65 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -111.10 | -- | -- | -- |
MoonLake Immunotherapeutics | 0.00 | -54.80m | 3.45bn | 50.00 | -- | 6.53 | -- | -- | -0.9043 | -0.9043 | 0.00 | 8.28 | 0.00 | -- | -- | 0.00 | -11.08 | -- | -11.49 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 27.95 | -- | -- | -- |
Dyne Therapeutics Inc | 0.00 | -257.60m | 3.67bn | 152.00 | -- | 4.73 | -- | -- | -3.58 | -3.58 | 0.00 | 7.74 | 0.00 | -- | -- | 0.00 | -47.82 | -52.81 | -50.15 | -57.45 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -40.36 | -- | 40.32 | -- |
TG Therapeutics Inc | 346.73m | 95.69m | 3.82bn | 300.00 | 41.08 | 21.49 | 39.82 | 11.01 | 0.6001 | 0.6001 | 2.29 | 1.15 | 1.11 | 0.4505 | 6.86 | 1,313,356.00 | 30.76 | -62.87 | 43.42 | -80.06 | 92.76 | -- | 27.60 | -405.03 | 2.83 | 8.21 | 0.3661 | -- | 8,290.02 | 333.86 | 106.39 | -- | -- | -- |
Biohaven Ltd | 0.00 | -746.61m | 3.82bn | 239.00 | -- | 9.72 | -- | -- | -9.15 | -9.15 | 0.00 | 4.16 | 0.00 | -- | -- | 0.00 | -137.07 | -- | -176.64 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 28.43 | -- | -- | -- |
Crinetics Pharmaceuticals Inc | 1.39m | -258.54m | 4.25bn | 290.00 | -- | 5.07 | -- | 3,071.40 | -3.77 | -3.77 | 0.0201 | 10.47 | 0.0023 | -- | 0.4157 | 4,775.86 | -41.16 | -42.53 | -44.29 | -45.36 | -- | -- | -18,257.91 | -5,446.39 | -- | -- | 0.00 | -- | -15.28 | 10.57 | -30.88 | -- | 34.65 | -- |
Immunovant Inc | 0.00 | -272.55m | 4.28bn | 207.00 | -- | 7.85 | -- | -- | -1.92 | -1.92 | 0.00 | 3.73 | 0.00 | -- | -- | 0.00 | -57.93 | -- | -64.54 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -22.93 | -- | -- | -- |
Denali Therapeutics Inc | 1.27m | -419.65m | 4.43bn | 364.00 | -- | 3.19 | -- | 3,492.69 | -2.85 | -2.85 | 0.0085 | 9.69 | 0.0009 | -- | -- | 2,847.19 | -29.89 | -14.98 | -31.50 | -17.71 | -- | -- | -33,121.86 | -104.50 | -- | -- | 0.00 | -- | 204.74 | 20.67 | 55.45 | -- | 30.70 | -- |
Arcellx Inc | 144.75m | -53.89m | 4.66bn | 130.00 | -- | 9.53 | -- | 32.17 | -1.05 | -1.05 | 2.84 | 9.08 | 0.2132 | -- | -- | 1,113,423.00 | -7.94 | -38.82 | -9.68 | -45.41 | -- | -- | -37.23 | -339.38 | -- | -- | 0.038 | -- | -- | -- | 62.53 | -- | 113.86 | -- |
Alkermes Plc | 1.51bn | 457.54m | 4.70bn | 2.10k | 10.68 | 3.69 | 9.23 | 3.12 | 2.67 | 1.69 | 8.78 | 7.74 | 0.6864 | 1.31 | 4.28 | 718,055.30 | 20.83 | 1.34 | 26.98 | 1.74 | 83.31 | 83.32 | 30.34 | 2.12 | 2.61 | -- | 0.184 | 0.00 | 49.61 | 8.74 | 1,665.99 | -- | -7.10 | -- |
Madrigal Pharmaceuticals Inc | 14.64m | -510.45m | 5.07bn | 376.00 | -- | 5.91 | -- | 346.34 | -25.50 | -25.50 | 0.7351 | 39.50 | 0.0209 | -- | -- | 38,930.85 | -72.80 | -62.09 | -86.71 | -74.81 | 95.66 | -- | -3,487.13 | -- | 8.67 | -- | 0.1198 | -- | -- | -- | -26.50 | -- | 132.01 | -- |
Krystal Biotech Inc | 166.23m | 105.94m | 5.29bn | 229.00 | 50.41 | 6.30 | 46.89 | 31.83 | 3.65 | 3.65 | 5.70 | 29.22 | 0.2076 | -- | -- | 725,908.30 | 13.23 | -11.50 | 14.07 | -12.01 | 93.07 | -- | 63.73 | -492.85 | 9.33 | -- | 0.00 | -- | -- | -- | 107.81 | -- | 39.49 | -- |
Ultragenyx Pharmaceutical Inc | 481.30m | -585.12m | 5.41bn | 1.28k | -- | 12.52 | -- | 11.25 | -7.29 | -7.29 | 5.95 | 4.69 | 0.3286 | 1.81 | 5.45 | 377,196.70 | -39.94 | -33.35 | -48.51 | -38.30 | 87.15 | 93.13 | -121.57 | -154.71 | 3.39 | -- | 0.00 | -- | 19.52 | 53.18 | 14.25 | -- | 62.91 | -- |
Holder | Shares | % Held |
---|---|---|
Baillie Gifford & Co.as of 30 Jun 2024 | 13.76m | 9.61% |
The Vanguard Group, Inc.as of 30 Jun 2024 | 11.00m | 7.68% |
BlackRock Fund Advisorsas of 30 Jun 2024 | 9.88m | 6.90% |
Wellington Management Co. LLPas of 30 Jun 2024 | 9.72m | 6.79% |
Capital Research & Management Co. (Global Investors)as of 30 Jun 2024 | 7.13m | 4.98% |
Temasek Holdings Pte Ltd. (Investment Management)as of 30 Jun 2024 | 5.71m | 3.99% |
Crestline Management LPas of 30 Jun 2024 | 4.76m | 3.33% |
SSgA Funds Management, Inc.as of 30 Jun 2024 | 4.43m | 3.10% |
Baker Bros. Advisors LPas of 30 Jun 2024 | 3.73m | 2.61% |
Geode Capital Management LLCas of 30 Jun 2024 | 2.98m | 2.08% |