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About the company
Opus Genetics, Inc. is a clinical-stage ophthalmic biotechnology company. The Company is engaged in developing gene therapies for the treatment of inherited retinal diseases (IRDs) and other types of therapies for additional ophthalmic disorders. The Company’s pipeline includes adeno-associated virus (AAV)-based investigational gene therapies that address mutations in genes that cause different forms of bestrophinopathy, Leber congenital amaurosis (LCA) and retinitis pigmentosa. Its pipeline also includes OPGx-BEST1 investigational gene therapy, designed to address mutations in the BEST1 gene, which is associated with retinal degeneration. The pipeline also includes Phentolamine Ophthalmic Solution 0.75%, a non-selective alpha-1 and alpha-2 adrenergic antagonist being investigated to reduce pupil size, and APX3330, a novel small-molecule inhibitor of Ref-1 being investigated to slow the progression of non-proliferative diabetic retinopathy.
- Revenue in USD (TTM)14.63m
- Net income in USD-68.20m
- Incorporated2005
- Employees18.00
- LocationOpus Genetics Inc8 Davis Drive, Suite 220DURHAM 27709United StatesUSA
- Phone+1 (248) 681-9815
- Fax+1 (302) 636-5454
- Websitehttps://opusgtx.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sanara Medtech Inc | 101.90m | -6.24m | 174.42m | 141.00 | -- | 28.35 | -- | 1.71 | -0.7292 | -4.34 | 11.86 | 0.6885 | 1.28 | 2.47 | 8.78 | 722,724.30 | -8.03 | -15.12 | -10.00 | -18.64 | 92.25 | 88.92 | -6.29 | -14.70 | 1.60 | 0.3039 | 0.8801 | -- | 33.36 | 49.09 | -124.59 | -- | -33.05 | -- |
| Tonix Pharmaceuticals Holding Corp | 10.30m | -99.22m | 203.55m | 81.00 | -- | 0.6999 | -- | 19.76 | -20.11 | -20.11 | 1.69 | 22.73 | 0.0593 | 0.9665 | 2.75 | 127,148.10 | -57.12 | -61.84 | -63.76 | -68.67 | 34.31 | -- | -963.38 | -2,797.35 | 9.62 | -- | 0.00 | -- | 29.94 | -- | -11.47 | -- | 47.82 | -- |
| BGM Group Ltd | 26.85m | -2.72m | 216.07m | 323.00 | -- | 0.7178 | -- | 8.05 | -0.2816 | -0.2816 | 1.38 | 1.85 | 0.2087 | 3.21 | 8.60 | 83,116.91 | -2.08 | -0.0792 | -2.36 | -0.1065 | 19.41 | 10.38 | -9.95 | -0.0921 | 1.45 | -0.3408 | 0.0087 | 2,560.18 | -45.99 | -11.45 | 81.46 | -- | 16.40 | -- |
| Journey Medical Corp | 59.40m | -8.66m | 220.78m | 41.00 | -- | 8.25 | -- | 3.72 | -0.3645 | -0.3645 | 2.58 | 0.982 | 0.796 | 1.79 | 4.15 | 1,448,756.00 | -11.61 | -22.37 | -22.74 | -50.55 | 64.40 | 59.45 | -14.58 | -27.43 | 1.12 | -3.30 | 0.4928 | -- | -29.11 | 9.96 | -280.79 | -- | 44.27 | -- |
| Mediwound Ltd | 20.93m | -20.60m | 225.77m | 111.00 | -- | 4.50 | -- | 10.79 | -1.90 | -1.90 | 1.93 | 3.91 | 0.2475 | 4.59 | 3.69 | 188,576.60 | -24.36 | -35.38 | -35.12 | -48.39 | 18.53 | 32.18 | -98.43 | -71.55 | 2.48 | -- | 0.1416 | -- | 8.22 | -8.65 | -350.03 | -- | 51.27 | -- |
| Opus Genetics Inc | 14.63m | -68.20m | 240.69m | 18.00 | -- | 37.75 | -- | 16.45 | -1.76 | -1.76 | 0.2952 | 0.0925 | 0.3825 | -- | 3.85 | 812,944.40 | -178.28 | -76.30 | -330.00 | -86.90 | -- | -- | -466.09 | -185.79 | -- | -- | 0.1518 | -- | -42.30 | -- | -476.13 | -- | -- | -- |
| Coherus Oncology Inc | 83.57m | -187.47m | 255.04m | 161.00 | -- | 2.79 | -- | 3.05 | -1.62 | 1.33 | 0.721 | 0.7551 | 0.1636 | 1.76 | 0.9453 | 366,526.30 | -36.70 | -21.44 | -106.02 | -31.54 | 47.79 | 71.26 | -224.34 | -42.66 | 1.23 | -15.12 | 0.3656 | -- | 3.78 | -5.60 | 111.98 | -20.51 | -- | -- |
| Fennec Pharmaceuticals Inc | 38.79m | -6.94m | 266.06m | 36.00 | -- | -- | -- | 6.86 | -0.2524 | -0.2524 | 1.41 | -0.1601 | 0.7171 | 1.48 | 2.41 | -- | -12.83 | -55.15 | -15.26 | -64.98 | 93.12 | -- | -17.89 | -107.31 | 4.44 | -2.44 | 1.33 | -- | 123.69 | -- | 97.28 | -- | -- | -- |
| Lifecore Biomedical Inc | -100.00bn | -100.00bn | 276.50m | 406.00 | -- | -- | -- | -- | -- | -- | -- | 0.9818 | -- | -- | -- | -- | -- | -7.91 | -- | -10.85 | -- | 32.86 | -- | -23.15 | 1.67 | -- | 0.787 | -- | 0.4725 | -4.24 | -575.39 | -- | -12.85 | -- |
| Abeona Therapeutics Inc | 400.00k | 82.35m | 277.46m | 136.00 | 4.63 | 1.57 | 3.28 | 693.65 | 1.11 | 1.11 | 0.0073 | 3.27 | 0.0023 | -- | 0.2478 | 2,941.18 | 46.83 | -62.23 | 52.94 | -78.23 | -122.00 | -- | 20,587.50 | -1,824.21 | 9.53 | -- | 0.1034 | -- | -100.00 | -- | -17.62 | -- | -17.78 | -- |
| Evolus Inc | 285.82m | -58.56m | 288.45m | 329.00 | -- | -- | -- | 1.01 | -0.9125 | -0.9125 | 4.46 | -0.4441 | 1.27 | 4.09 | 6.01 | 860,912.60 | -26.11 | -37.04 | -36.48 | -57.14 | 65.83 | 65.19 | -20.49 | -51.26 | 1.53 | -2.13 | 1.25 | -- | 31.76 | 50.12 | 18.26 | -- | 1.10 | -- |
| AC Immune SA | 5.69m | -93.60m | 307.26m | 133.00 | -- | 3.78 | -- | 53.97 | -0.9314 | -0.9314 | 0.0567 | 0.8099 | 0.021 | -- | 0.3392 | 42,807.89 | -34.57 | -27.41 | -66.37 | -30.60 | -- | -- | -1,643.94 | -505.58 | -- | -- | 0.0695 | -- | 84.51 | -24.38 | 6.12 | -- | -21.11 | -- |
| X4 Pharmaceuticals Inc | 33.98m | -95.10m | 324.39m | 143.00 | -- | 1.51 | -- | 9.55 | -10.50 | -10.50 | 2.94 | 2.45 | 0.1989 | 1.75 | 25.37 | 237,615.40 | -55.66 | -55.04 | -65.82 | -63.45 | 83.24 | -- | -279.86 | -6,897.81 | 5.48 | -19.26 | 0.5525 | -- | -- | -- | 62.98 | -- | 111.28 | -- |
| Puma Biotechnology Inc | 212.00m | 36.98m | 333.09m | 172.00 | 8.92 | 2.89 | 6.92 | 1.57 | 0.7414 | 0.7414 | 4.23 | 2.29 | 1.00 | 8.06 | 4.81 | 1,232,529.00 | 17.46 | -3.25 | 32.09 | -5.70 | 76.91 | 75.67 | 17.44 | -3.18 | 1.62 | 8.84 | 0.2263 | -- | -2.19 | -3.28 | 40.23 | -- | -28.80 | -- |
Data as of Feb 11 2026. Currency figures normalised to Opus Genetics Inc's reporting currency: US Dollar USD
21.80%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Perceptive Advisors LLCas of 30 Sep 2025 | 4.33m | 6.27% |
| Nantahala Capital Management LLCas of 30 Sep 2025 | 3.35m | 4.85% |
| The Vanguard Group, Inc.as of 31 Dec 2025 | 2.03m | 2.95% |
| Mink Brook Asset Management LLCas of 30 Sep 2025 | 1.24m | 1.80% |
| Opaleye Management, Inc.as of 30 Sep 2025 | 1.10m | 1.60% |
| Adage Capital Management LPas of 30 Sep 2025 | 955.00k | 1.39% |
| Bleichroeder LPas of 30 Sep 2025 | 736.84k | 1.07% |
| Voss Capital LPas of 30 Sep 2025 | 562.38k | 0.82% |
| Geode Capital Management LLCas of 30 Sep 2025 | 468.94k | 0.68% |
| Vanguard Fiduciary Trust Co.as of 31 Dec 2025 | 267.64k | 0.39% |
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Data from 30 Sep 2025 - 31 Dec 2025Source: FactSet Research Systems Inc.
