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About the company
Stoke Therapeutics, Inc. is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with ribonucleic acid (RNA)-based medicines. The Company, through its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach, is engaged in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its first compound, STK-001, is in clinical testing for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy. TANGO aims to restore missing proteins by increasing or stoking protein output from healthy genes, thus compensating for the non-functioning copy of the gene. The Company is pursuing the development of STK-002 for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. The Company’s initial focus is haploinsufficiency and diseases of the central nervous system and the eye.
- Revenue in USD (TTM)15.16m
- Net income in USD-103.57m
- Incorporated2014
- Employees110.00
- LocationStoke Therapeutics Inc45 WIGGINS AVENUEBEDFORD 01730United StatesUSA
- Phone+1 (781) 430-8200
- Fax+1 (302) 531-3150
- Websitehttps://www.stoketherapeutics.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adaptive Biotechnologies Corp | 168.77m | -213.47m | 685.75m | 709.00 | -- | 2.84 | -- | 4.06 | -1.47 | -1.47 | 1.16 | 1.64 | 0.2501 | 4.74 | 5.03 | 238,033.80 | -31.65 | -19.69 | -36.63 | -22.06 | 54.77 | 67.18 | -126.55 | -122.27 | 3.84 | -- | 0.3536 | -- | -8.11 | 25.06 | -12.52 | -- | 11.11 | -- |
| Ironwood Pharmaceuticals, Inc. | 400.57m | 9.21m | 686.88m | 267.00 | 99.51 | -- | 74.49 | 1.71 | 0.0432 | 0.0432 | 2.43 | -2.01 | 0.8021 | -- | 4.52 | 1,500,244.00 | 1.44 | -4.54 | 2.21 | -5.20 | -- | -- | 1.79 | -7.81 | -- | 4.60 | 2.07 | -- | 7.83 | 5.02 | -672.50 | -- | 160.10 | -- |
| Wave Life Sciences Ltd | 110.50m | -73.74m | 708.51m | 266.00 | -- | -- | -- | 6.41 | -0.5796 | -0.5796 | 0.9275 | 0.0359 | 0.5036 | -- | -- | 415,413.50 | -33.49 | -56.98 | -117.16 | -102.38 | -- | -- | -66.50 | -353.20 | -- | -- | 0.00 | -- | 3,005.10 | 51.04 | 64.46 | -- | -35.44 | -- |
| ProKidney Corp | 0.00 | -38.68m | 712.60m | 163.00 | -- | -- | -- | -- | -0.5905 | -0.5905 | 0.00 | -7.73 | 0.00 | -- | -- | 0.00 | -27.97 | -- | -- | -- | -- | -- | -- | -- | -- | -- | 0.0003 | -- | -- | -- | 67.17 | -- | -- | -- |
| Astria Therapeutics Inc | 0.00 | -93.24m | 713.78m | 59.00 | -- | 2.76 | -- | -- | -2.30 | -2.30 | 0.00 | 6.32 | 0.00 | -- | -- | 0.00 | -32.43 | -64.48 | -33.78 | -68.34 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -40.62 | -- | -- | -- |
| MBX Biosciences Inc | 0.00 | -47.20m | 718.30m | 36.00 | -- | -- | -- | -- | -1.48 | -1.48 | 0.00 | 1.71 | -- | -- | -- | 0.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -24.60 | -- | -- | -- |
| Stoke Therapeutics Inc | 15.16m | -103.57m | 723.91m | 110.00 | -- | 2.96 | -- | 47.76 | -2.18 | -2.18 | 0.317 | 4.64 | 0.0537 | -- | 68.74 | 137,790.90 | -36.68 | -31.62 | -41.57 | -33.92 | -- | -- | -683.31 | -1,775.50 | -- | -- | 0.00 | -- | -29.22 | -- | -3.59 | -- | 11.56 | -- |
| Savara Inc | 0.00 | -75.29m | 739.06m | 37.00 | -- | 6.10 | -- | -- | -0.4317 | -0.4317 | 0.00 | 0.7361 | 0.00 | -- | -- | 0.00 | -58.02 | -36.86 | -62.14 | -39.54 | -- | -- | -- | -102,587.50 | -- | -- | 0.2066 | -- | -- | -- | -43.38 | -- | 15.91 | -- |
| Annexon Inc | 0.00 | -115.16m | 742.75m | 71.00 | -- | 2.05 | -- | -- | -1.22 | -1.22 | 0.00 | 3.42 | 0.00 | -- | -- | 0.00 | -36.04 | -44.06 | -38.13 | -46.93 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 5.43 | -- | 62.56 | -- |
| Replimune Group Inc | 0.00 | -220.01m | 745.39m | 331.00 | -- | 1.75 | -- | -- | -3.27 | -3.27 | 0.00 | 6.24 | 0.00 | -- | -- | 0.00 | -38.64 | -29.08 | -41.09 | -30.56 | -- | -- | -- | -- | -- | -- | 0.143 | -- | -- | -- | -23.82 | -- | 16.84 | -- |
| Scholar Rock Holding Corp | 0.00 | -203.85m | 751.51m | 150.00 | -- | 5.62 | -- | -- | -2.22 | -2.22 | 0.00 | 1.67 | 0.00 | -- | -- | 0.00 | -79.66 | -38.14 | -89.70 | -44.31 | -- | -- | -- | -647.95 | -- | -- | 0.2726 | -- | -100.00 | -- | -23.26 | -- | -45.61 | -- |
| Zenas Biopharma Inc | 50.00m | -54.76m | 756.06m | 114.00 | -- | -- | -- | 15.12 | -1.38 | -1.38 | 1.26 | 4.04 | -- | -- | -- | 595,238.10 | -- | -- | -- | -- | -- | -- | -109.51 | -- | -- | -- | 0.00 | -- | -- | -- | 68.88 | -- | -- | -- |
| Arbutus Biopharma Corp | 10.06m | -77.09m | 758.90m | 73.00 | -- | 6.20 | -- | 75.43 | -0.4416 | -0.4416 | 0.0575 | 0.6488 | 0.0597 | -- | 4.59 | 137,821.90 | -45.77 | -52.62 | -53.21 | -58.11 | -- | -- | -766.20 | -537.81 | -- | -- | 0.00 | -- | -53.51 | 25.00 | -4.89 | -- | -2.40 | -- |
| AbCellera Biologics Inc | 33.06m | -153.30m | 763.18m | 586.00 | -- | 0.6870 | -- | 23.09 | -0.5254 | -0.5254 | 0.1133 | 3.77 | 0.0224 | -- | 0.808 | 56,407.85 | -10.39 | 6.08 | -11.11 | 6.67 | -- | -- | -463.77 | 24.69 | -- | -- | 0.00 | 0.00 | -92.17 | 33.91 | -192.35 | -- | 70.96 | -- |
| Rapport Therapeutics Inc | -100.00bn | -100.00bn | 776.52m | 58.00 | -- | 2.30 | -- | -- | -- | -- | -- | 9.21 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -226.57 | -- | -- | -- |
Data as of Sep 20 2024. Currency figures normalised to Stoke Therapeutics Inc's reporting currency: US Dollar USD
63.69%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Lynx1 Capital Management LPas of 30 Jun 2024 | 5.19m | 9.85% |
| Redmile Group LLCas of 30 Jun 2024 | 4.72m | 8.97% |
| Baker Bros. Advisors LPas of 30 Jun 2024 | 4.37m | 8.30% |
| RTW Investments LPas of 30 Jun 2024 | 4.22m | 8.03% |
| Morgan Stanley & Co. LLCas of 30 Jun 2024 | 3.46m | 6.58% |
| TD Securities (USA) LLCas of 30 Jun 2024 | 3.37m | 6.39% |
| The Vanguard Group, Inc.as of 30 Jun 2024 | 2.59m | 4.91% |
| BlackRock Fund Advisorsas of 30 Jun 2024 | 2.41m | 4.58% |
| BlackRock Advisors LLCas of 30 Jun 2024 | 1.61m | 3.07% |
| SSgA Funds Management, Inc.as of 30 Jun 2024 | 1.59m | 3.02% |
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Data from 30 Jun 2024 - 30 Jun 2024Source: FactSet Research Systems Inc.
