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About the company
Tango Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to discovering novel drug targets and delivering precision medicine for the treatment of cancer. The Company's novel small molecules are designed to be selectively active in cancer cells with specific genetic alterations, killing those cancer cells while sparing normal cells. It is also extending its target space beyond the classic, cell-autonomous effects of tumor suppressor gene loss. It is engaged in developing two methylthioadenosine (MTA)-cooperative protein arginine methyltransferase 5 (PRMT5) inhibitors: TNG462 for non- central nervous system (CNS) cancers, including pancreatic and lung cancer, and TNG456, brain-penetrant PRMT5 inhibitor, for CNS cancers, including glioblastoma (GBM). Its TNG260 is a first-in-class Co-repressor of Repressor Element-1 Silencing Transcription (CoREST) inhibitor, which in preclinical studies reversed the immune evasion effect of STK11 loss-of-function mutations.
- Revenue in USD (TTM)66.50m
- Net income in USD-100.52m
- Incorporated2020
- Employees155.00
- LocationTango Therapeutics Inc201 Brookline Avenue, Suite 901BOSTON 02215United StatesUSA
- Phone+1 (857) 320-4900
- Fax+1 (302) 636-5454
- Websitehttps://www.tangotx.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BioCryst Pharmaceuticals Inc | 599.82m | -8.78m | 1.55bn | 580.00 | -- | -- | -- | 2.58 | -0.0473 | -0.0473 | 2.78 | -1.84 | 1.28 | 2.10 | 7.32 | 1,034,166.00 | -1.87 | -40.01 | -2.96 | -53.68 | 97.39 | 97.34 | -1.46 | -75.69 | 1.83 | 0.9698 | 2.35 | -- | 36.00 | 55.97 | 60.77 | -- | 26.79 | -- |
| Agios Pharmaceuticals Inc | 44.79m | -401.27m | 1.55bn | 486.00 | -- | 1.21 | -- | 34.59 | -6.96 | -6.96 | 0.7768 | 22.04 | 0.0282 | 0.1959 | 11.00 | 92,162.55 | -25.26 | -10.38 | -26.90 | -11.09 | 87.22 | -- | -895.86 | -768.40 | 13.39 | -- | 0.00 | -- | 36.07 | -- | 291.35 | -- | -32.66 | -- |
| Alvotech SA | 573.35m | 69.50m | 1.56bn | 1.01k | 23.84 | -- | 14.80 | 2.71 | 0.2093 | 0.2093 | 1.93 | -0.5671 | 0.434 | 1.53 | 4.30 | 567,111.80 | 5.26 | -- | 6.38 | -- | 55.59 | -- | 12.12 | -201.24 | 0.7376 | 2.57 | 1.16 | -- | 426.84 | 42.86 | 57.98 | -- | 47.91 | -- |
| Tyra Biosciences Inc | 0.00 | -111.68m | 1.57bn | 60.00 | -- | 5.60 | -- | -- | -1.88 | -1.88 | 0.00 | 5.26 | 0.00 | -- | -- | 0.00 | -32.73 | -24.74 | -34.14 | -25.67 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -25.09 | -- | 101.48 | -- |
| Sionna Therapeutics Inc | 0.00 | -70.68m | 1.57bn | 48.00 | -- | 4.87 | -- | -- | -1.61 | -1.61 | 0.00 | 7.23 | 0.00 | -- | -- | 0.00 | -26.35 | -- | -27.17 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -30.52 | -- | -- | -- |
| Corvus Pharmaceuticals Inc | 0.00 | -15.08m | 1.60bn | 31.00 | -- | 19.83 | -- | -- | -0.2004 | -0.2004 | 0.00 | 0.961 | 0.00 | -- | -- | 0.00 | -21.65 | -46.71 | -35.55 | -55.72 | -- | -- | -- | -- | -- | -38.28 | 0.00 | -- | -- | -- | -130.47 | -- | -- | -- |
| Definium Therapeutics Inc | 0.00 | -168.10m | 1.60bn | 74.00 | -- | 9.55 | -- | -- | -1.97 | -1.97 | 0.00 | 1.70 | 0.00 | -- | -- | 0.00 | -60.39 | -55.68 | -73.40 | -63.31 | -- | -- | -- | -- | -- | -- | 0.2362 | -- | -- | -- | -13.52 | -- | -- | -- |
| Enliven Therapeutics Inc | 0.00 | -97.21m | 1.60bn | 65.00 | -- | 3.36 | -- | -- | -1.85 | -1.85 | 0.00 | 8.03 | 0.00 | -- | -- | 0.00 | -24.41 | -35.02 | -25.43 | -38.16 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -24.36 | -- | -20.66 | -- |
| Tango Therapeutics Inc | 66.50m | -100.52m | 1.61bn | 155.00 | -- | 8.33 | -- | 24.19 | -0.9208 | -0.9208 | 0.593 | 1.43 | 0.2364 | -- | -- | 429,038.70 | -35.74 | -- | -39.69 | -- | -- | -- | -151.15 | -283.69 | -- | -- | 0.00 | -- | 15.17 | -- | -28.07 | -- | -- | -- |
| Pharvaris NV | 0.00 | -192.78m | 1.61bn | 108.00 | -- | 4.44 | -- | -- | -3.44 | -3.44 | 0.00 | 5.66 | 0.00 | -- | -- | 0.00 | -50.22 | -36.71 | -53.72 | -38.87 | -- | -- | -- | -- | -- | -- | 0.0019 | -- | -- | -- | -33.06 | -- | 109.04 | -- |
| MBX Biosciences Inc | 0.00 | -80.50m | 1.62bn | 43.00 | -- | 4.16 | -- | -- | -3.39 | -3.39 | 0.00 | 8.67 | 0.00 | -- | -- | 0.00 | -23.59 | -- | -24.41 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -90.16 | -- | -- | -- |
| Nurix Therapeutics Inc | 83.98m | -264.46m | 1.64bn | 317.00 | -- | 3.01 | -- | 19.53 | -3.04 | -3.04 | 0.969 | 5.29 | 0.1237 | -- | -- | 264,921.10 | -38.96 | -36.56 | -45.01 | -43.34 | -- | -- | -314.90 | -316.85 | -- | -- | 0.00 | -- | 53.95 | 36.35 | -36.62 | -- | 25.19 | -- |
| Zymeworks Inc | 134.48m | -63.43m | 1.65bn | 263.00 | -- | 5.21 | -- | 12.25 | -0.8448 | -0.8448 | 1.78 | 4.23 | 0.3041 | -- | 5.07 | 480,289.30 | -14.34 | -19.80 | -16.73 | -23.38 | -- | -- | -47.16 | -80.81 | -- | -- | 0.00 | -- | 0.3842 | 20.90 | -3.39 | -- | -26.07 | -- |
| Rapt Therapeutics Inc | 0.00 | -105.64m | 1.67bn | 60.00 | -- | 6.40 | -- | -- | -11.08 | -11.08 | 0.00 | 9.02 | 0.00 | -- | -- | 0.00 | -77.05 | -49.22 | -84.35 | -54.31 | -- | -- | -- | -4,359.44 | -- | -- | 0.00 | -- | -- | -- | -11.19 | -- | -32.77 | -- |
Data as of Feb 06 2026. Currency figures normalised to Tango Therapeutics Inc's reporting currency: US Dollar USD
47.51%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Farallon Capital Management LLCas of 30 Sep 2025 | 10.76m | 7.99% |
| EcoR1 Capital, LLCas of 30 Sep 2025 | 10.63m | 9.56% |
| Boxer Capital Management LLCas of 30 Sep 2025 | 9.77m | 7.26% |
| Woodline Partners LPas of 30 Sep 2025 | 6.03m | 4.48% |
| The Vanguard Group, Inc.as of 31 Dec 2025 | 6.01m | 4.46% |
| BlackRock Fund Advisorsas of 30 Sep 2025 | 5.11m | 3.79% |
| T. Rowe Price Investment Management, Inc.as of 30 Sep 2025 | 3.53m | 2.62% |
| Balyasny Asset Management LPas of 30 Sep 2025 | 3.47m | 2.58% |
| SSgA Funds Management, Inc.as of 30 Sep 2025 | 3.37m | 2.50% |
| Paradigm BioCapital Advisors LPas of 30 Sep 2025 | 3.09m | 2.29% |
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Data from 30 Sep 2025 - 31 Dec 2025Source: FactSet Research Systems Inc.
