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About the company
X4 Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on discovering and developing novel therapeutics for the treatment of rare diseases and those with limited treatment options, with a focus on conditions resulting from dysfunction of the immune system. Its lead clinical candidate is mavorixafor, a small-molecule selective antagonist of chemokine receptor CXCR4. It has developed a small-molecule, oral antagonists of the chemokine receptor C-X-C receptor type 4 (CXCR4). It has two pre-clinical candidates: X4P-003, a second-generation CXCR4 antagonist designed to have enhanced properties relative to mavorixafor, potentially enabling opportunities in CXCR4-dependent disorders and primary immunodeficiencies, and X4P-002, a CXCR4 antagonist with a distribution profile and a demonstrated ability to cross the blood-brain barrier.
- Revenue in USD (TTM)33.98m
- Net income in USD-95.10m
- Incorporated2010
- Employees143.00
- LocationX4 Pharmaceuticals Inc61 NORTH BEACON STREET, 4TH FLOORBOSTON 02134United StatesUSA
- Phone+1 (857) 529-8300
- Fax+1 (302) 655-5049
- Websitehttps://www.x4pharma.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mediwound Ltd | 20.93m | -20.60m | 230.39m | 111.00 | -- | 4.59 | -- | 11.01 | -1.90 | -1.90 | 1.93 | 3.91 | 0.2475 | 4.59 | 3.69 | 188,576.60 | -24.36 | -35.38 | -35.12 | -48.39 | 18.53 | 32.18 | -98.43 | -71.55 | 2.48 | -- | 0.1416 | -- | 8.22 | -8.65 | -350.03 | -- | 51.27 | -- |
| Opus Genetics Inc | 14.63m | -68.20m | 233.10m | 18.00 | -- | 36.56 | -- | 15.93 | -1.76 | -1.76 | 0.2952 | 0.0925 | 0.3825 | -- | 3.85 | 812,944.40 | -178.28 | -76.30 | -330.00 | -86.90 | -- | -- | -466.09 | -185.79 | -- | -- | 0.1518 | -- | -42.30 | -- | -476.13 | -- | -- | -- |
| Coherus Oncology Inc | 83.57m | -187.47m | 248.99m | 161.00 | -- | 2.73 | -- | 2.98 | -1.62 | 1.33 | 0.721 | 0.7551 | 0.1636 | 1.76 | 0.9453 | 366,526.30 | -36.70 | -21.44 | -106.02 | -31.54 | 47.79 | 71.26 | -224.34 | -42.66 | 1.23 | -15.12 | 0.3656 | -- | 3.78 | -5.60 | 111.98 | -20.51 | -- | -- |
| Fennec Pharmaceuticals Inc | 38.79m | -6.94m | 268.45m | 36.00 | -- | -- | -- | 6.92 | -0.2524 | -0.2524 | 1.41 | -0.1601 | 0.7171 | 1.48 | 2.41 | -- | -12.83 | -55.15 | -15.26 | -64.98 | 93.12 | -- | -17.89 | -107.31 | 4.44 | -2.44 | 1.33 | -- | 123.69 | -- | 97.28 | -- | -- | -- |
| Evolus Inc | 285.82m | -58.56m | 274.84m | 329.00 | -- | -- | -- | 0.9616 | -0.9125 | -0.9125 | 4.46 | -0.4441 | 1.27 | 4.09 | 6.01 | 860,912.60 | -26.11 | -37.04 | -36.48 | -57.14 | 65.83 | 65.19 | -20.49 | -51.26 | 1.53 | -2.13 | 1.25 | -- | 31.76 | 50.12 | 18.26 | -- | 1.10 | -- |
| Abeona Therapeutics Inc | 400.00k | 82.35m | 278.00m | 136.00 | 4.64 | 1.57 | 3.28 | 695.00 | 1.11 | 1.11 | 0.0073 | 3.27 | 0.0023 | -- | 0.2478 | 2,941.18 | 46.83 | -62.23 | 52.94 | -78.23 | -122.00 | -- | 20,587.50 | -1,824.21 | 9.53 | -- | 0.1034 | -- | -100.00 | -- | -17.62 | -- | -17.78 | -- |
| Lifecore Biomedical Inc | -100.00bn | -100.00bn | 279.50m | 406.00 | -- | -- | -- | -- | -- | -- | -- | 0.9818 | -- | -- | -- | -- | -- | -7.91 | -- | -10.85 | -- | 32.86 | -- | -23.15 | 1.67 | -- | 0.787 | -- | 0.4725 | -4.24 | -575.39 | -- | -12.85 | -- |
| X4 Pharmaceuticals Inc | 33.98m | -95.10m | 310.40m | 143.00 | -- | 1.45 | -- | 9.14 | -10.50 | -10.50 | 2.94 | 2.45 | 0.1989 | 1.75 | 25.37 | 237,615.40 | -55.66 | -55.04 | -65.82 | -63.45 | 83.24 | -- | -279.86 | -6,897.81 | 5.48 | -19.26 | 0.5525 | -- | -- | -- | 62.98 | -- | 111.28 | -- |
| AC Immune SA | 5.71m | -93.84m | 312.28m | 133.00 | -- | 3.83 | -- | 54.71 | -0.9339 | -0.9339 | 0.0568 | 0.812 | 0.021 | -- | 0.3392 | 42,919.68 | -34.57 | -27.41 | -66.37 | -30.60 | -- | -- | -1,643.94 | -505.58 | -- | -- | 0.0695 | -- | 84.51 | -24.38 | 6.12 | -- | -21.11 | -- |
| Puma Biotechnology Inc | 212.00m | 36.98m | 346.69m | 172.00 | 9.28 | 3.01 | 7.21 | 1.64 | 0.7414 | 0.7414 | 4.23 | 2.29 | 1.00 | 8.06 | 4.81 | 1,232,529.00 | 17.46 | -3.25 | 32.09 | -5.70 | 76.91 | 75.67 | 17.44 | -3.18 | 1.62 | 8.84 | 0.2263 | -- | -2.19 | -3.28 | 40.23 | -- | -28.80 | -- |
| Eton Pharmaceuticals Inc | 70.32m | -6.68m | 397.17m | 31.00 | -- | 17.17 | -- | 5.65 | -0.2491 | -0.2491 | 2.63 | 0.8624 | 1.00 | 3.64 | 7.53 | 2,268,258.00 | -9.52 | -27.81 | -17.48 | -37.96 | 51.36 | 68.16 | -9.50 | -38.41 | 1.25 | 0.2114 | 0.5677 | -- | 23.29 | 109.83 | -308.44 | -- | 40.24 | -- |
| Akebia Therapeutics Inc | 225.07m | -15.91m | 398.05m | 181.00 | -- | 9.57 | -- | 1.77 | -0.0761 | -0.0761 | 0.8951 | 0.1568 | 0.7879 | 2.08 | 4.57 | 1,243,486.00 | -5.57 | -38.92 | -8.55 | -61.07 | 81.89 | 71.93 | -7.07 | -76.49 | 1.80 | 0.7147 | 0.8219 | -- | -17.70 | -13.72 | -33.67 | -- | -65.40 | -- |
Data as of Feb 10 2026. Currency figures normalised to X4 Pharmaceuticals Inc's reporting currency: US Dollar USD
40.48%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Empery Asset Management LPas of 31 Dec 2025 | 8.95m | 10.24% |
| Fidelity Management & Research Co. LLCas of 31 Oct 2025 | 8.50m | 9.72% |
| Perceptive Advisors LLCas of 27 Oct 2025 | 5.91m | 6.76% |
| The Vanguard Group, Inc.as of 31 Dec 2025 | 2.91m | 3.33% |
| BVF Partners LPas of 30 Sep 2025 | 2.23m | 2.56% |
| Nantahala Capital Management LLCas of 30 Sep 2025 | 2.23m | 2.55% |
| Rosalind Advisors, Inc.as of 30 Sep 2025 | 1.54m | 1.77% |
| Deep Track Capital LPas of 30 Sep 2025 | 1.12m | 1.28% |
| Stonepine Capital Management LLCas of 30 Sep 2025 | 1.06m | 1.21% |
| Kingdon Capital Management LLCas of 30 Sep 2025 | 933.33k | 1.07% |
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Data from 30 Sep 2025 - 01 Jan 2026Source: FactSet Research Systems Inc.
